The Base - NMN

+ What is NMN?

NMN is short for β-Nicotinamide Mononucleotide. It is derived from ribose, sugar and vitamin B3. It boosts your body’s NAD+ production, which in turn has numerous health benefits, primarily fighting ageing.

+ Why should I take NMN?

Scientific studies have shown that NMN can improve many symptoms of ageing in various organisms. NMN improves healthy ageing by boosting NAD+ levels. NAD+ is needed to repair our DNA and maintain overall cellular health. As we age, NAD+ levels go down and supplementing NMN can maintain these NAD+ levels. This helps to repair your DNA, boosts your cellular health and supports 5 Hallmarks of Ageing.

+ Have clinical trials been conducted on NMN?

Yes. We list the scientific studies done on NMN on this dedicated page: click here.

+ Is there any human data available on NMN? Has it been published?

Yes. Multiple studies have been done on humans showing that it's safe for human consumption and is effective in raising NAD+levels. We list the scientific studies done on NMN on this dedicated page: click here.

+ Is NMN safe?

NMN naturally occurs in the human body and has been deemed safe for human consumption in a 2020 Japanese human trial, see the scientific article. Our NMN has been tested for heavy metals and purity, see our testing reports. We do not recommend taking NMN when you are pregnant or are suffering from serious diseases. When in doubt, always seek the advice of a health/medical professional.

+ Where is The Base - NMN made?

We have created The Base with Longevir™ NMN, from the only supplier in the world that makes NMN 100% in Europe. The Base is also encapsulated in the EU and finally bottled in Singapore.

We produce our products in accordance with the current Good Manufacturing Practices (cGMPs), which require our manufacturers to adhere to regulations that ensure the identity, strength, quality, and purity of our products. Our manufacturer is a GMP-certified facility in the United States of America.

+ What are the ingredients in The Base - NMN?

The Base - NMN contains the compound Nicotinamide Mononucleotide ( NMN in short), or Longevir™ NMN. NMN is a molecule that is found naturally in the human body, but can also be found in foods such as cabbage, cucumber, soy beans, avocado and broccoli. It is a compound of nicotinamide (a form of vitamin B3), ribose (a sugar molecule) and a phosphate molecule.

+ What does 99% purity mean and what is the other 1%?

The Base - NMN contains the highest possible level of purity at 99%. NMN is extracted from natural ingredients and, due to the nature of the extraction process, 1% does not get converted into NMN. The remaining 1% is a form of vitamin B3 called NAM (Nicotinamide) which also is a NAD+ precursor. NAM can still get converted into NMN in your body, which then again boosts your NAD+ levels.

+ What is the best time of the day to take NMN?

NMN is best taken in the morning, on an empty stomach. After you wake up, you're NAD+ levels start rising and taking NMN in the morning therefore gives this process the extra well-needed boost.

+ What daily dosage do you recommend?

We recommended a dosage of NMN of 250 mg per day (1 pill per day). This dosage has been proven to increase NAD+ levels adequately. Most human clinical studies currently underway are also working with a daily dosage of 250 mg. People in higher age groups (45 and older) might benefit from higher dosages, but research is still pending. Note that NMN has been tested for safety for doses up to 500 mg per day. Read more about what dose might be suitable for you on our blog post.

+ How strong is the proof that NMN is actually working?

NMN has gained a lot of attention in the past few years, especially after the release of Harvard professor David Sinclair's book Lifespan in 2019.

David Sinclair is very open about using NMN himself and talks about several use cases of other people taking NMN and what effects they have noticed.

In his book, David Sinclair discusses that boosting NAD+ levels through NMN administration extends the life of several organisms, including yeast, worms, and mice. Administration of NMN has shown positive effects on age-related issues, such as skin health, energy levels and cognitive health in test subjects. However, human efficacy trials are still in their infancy.

A few human trials have been conducted and several are ongoing. NMN has been proven to be safe in humans, effectively raises NAD+ levels in humans and recent studies show positive effects on exercise endurance and insulin sensitivity.

+ Does NMN have any side effects?

Human trials have been conducted to research the safety of NMN and no side effects of nicotinamide mononucleotide have been documented. The clinical trials on humans revealed no safety concern following single oral doses up to 500 mg. Our recommended dosage is 250mg (1 pill) of NMN per day.

+ Is NMN a natural or artificial product?

The active ingredient in The Base - NMN is β-Nicotinamide Mononucleotide, which is naturally found in milk and green vegetables like broccoli. The NMN in The Base - NMN is manufactured in higher quantities, but is molecularly identical to the NMN found in green vegetables.

+ Does The Base - NMN contain dairy, tree nuts, soy, or gluten?

No, The Base - NMN is dairy-free, tree-nut free, soy-free, and gluten-free.

+ Is The Base - NMN vegetarian?

Yes, The Base-NMN is vegetarian.

+ Can I take NMN alongside other supplements?

There shouldn’t be any issues taking multiple supplements alongside NMN; there are no known (negative) interactions with other supplements. NMN is a compound which already occurs naturally in the human body and is a vitamine B3 derivative.

To assess whether specific supplements interact with NMN, we would recommend talking to a health professional before you start taking NMN.

+ How is The Base - NMN different from other anti-ageing skin products?

Anti-ageing products are often applied topically (on the skin) and lead to cosmetic, visual changes. Your skin may look better but the root causes of your ageing skin are not addressed. For example, hyaluronic acid cannot permeate the skin when applied topically; the best it can do is to create a tiny layer on the outside of the skin which holds moisture.

The Base - NMN is different in the way that it improves your skin from the inside out, making your skin look healthier and younger. NMN targets the signs of ageing by treating the underlying causes on a cellular level, throughout your entire body.

+ When can I expect to see results?

This varies. People who start taking NMN normally notice an improved skin condition, and increased energy in the first weeks of taking NMN. Improved neurological function and improved muscle strength are often reported after a few weeks to a few months.

+ Which results can I expect?

The rejuvenation by NMN is difficult to see at first. The most common early reported results are increased hair growth, improved skin condition, increased energy, improved neurological function, and improved muscle strength.

+ At which age should I start taking NMN?

The Base-NMN is intended for healthy adults, ages 18 and up. NMN is a NAD+ booster and levels of NAD+ go down as you age. The older you get, the lower the levels. There is not one certain age specified to start taking NMN. However if you are noticing the first signs of ageing (like dull skin, declining energy levels) and you want to slow down this process, it would be a good idea to start taking NMN.

For Youth has also recently launched a biological age test. Taking such a test could give insight in your rate of ageing and therefore whether you want to satar

+ Is NMN better than NR?

The scientific debate about whether NMN is better than NR or vice versa is still ongoing, but NMN has some convincing arguments to win the debate: NMN is one step further in the pathway that converts NAD+ boosters (like NMN and NR) into NAD. NR is converted into NMN, and then NMN is used to build NAD+. NMN is more easily absorbed in the blood. The scientific studies with NMN are showing better results. Please find more info about the scientific studies which have been conducted on our dedicated NMN science page: click here.

+ How do I store my supplements?

Store supplements in a cool, dark, and dry place, away from direct sunlight and humidity.

+ Should I keep The Base - NMN in the fridge?

The NMN we sell is a stabilised form. It is produced including three crystallisation stages to get the highest level of bioavailability. That’s why our NMN is 99% pure. Another advantage is that high temperatures do not have a big effect on potency. Recent research for stable forms of NMN shows that exposing NMN for 6 months to around 44 degrees Celsius only caused a loss of 3% in potency.

Although the effect is limited, we do recommend storing NMN in a cool place to keep the best condition for a longer time.

+ Will my body get physically dependent on NMN after taking it for a while?

When you stop taking NMN your body's NAD+ levels will return to the levels produced by your body that are normal for your age. NMN is a vitamin B3 derivative that is actually in the human body from vitamin B3 in the form of nicotinamide. Taking NMN can therefore not be compared to hormone therapies that create dependencies. There are no adverse effects (such as accelerated ageing) when you stop taking NMN.

+ Can I take The Base - NMN if I am pregnant or nursing?

We do not recommend taking The Base-NMN during pregnancy or while nursing.

+ I have concerns about taking The Base - NMN with my other medicines or supplements.

Please consult with your healthcare provider before starting a supplement regimen.

+ What information should I share with my physician?

We encourage you to share information from our product page and science pages with your healthcare provider.